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Internal Medicine

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A young cis-gender woman is diagnosed with pharyngeal gonorrhea.


Which of the following antimicrobials has the highest efficacy when treating this infection?

  • Cefixime

  • Ceftriaxone

  • Doxycycline

  • Spectinomycin


Currently, the only recommended treatment regimen for pharyngeal gonorrhea is ceftriaxone 500 mg intramuscularly. No other regimen is recommended by the CDC. All patients treated for pharyngeal gonorrhea must have a test of cure nucleic acid amplification test (NAAT) of the pharynx performed one to two weeks after treatment. If antimicrobial resistance is suspected, a pharyngeal sample for culture and antimicrobial susceptibility testing  should also be sent. @Everyone

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