Based on the CLASSIC trial. how did your fluid management of sepsis changed?
No changes, give 30 mL/kg bolus if hypotensive or LA >4
Restrict to 250-500 mL bolus based on the study criteria!
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Infectious Disease & Sepsis
Public·430 members
In a study among 14-hospital integrated system in Pittsburgh that was published in JAMA, source control intervention within 6 hours of presentation in 4962 patients with community-acquired sepsis, was associated with 29% risk-adjusted 90-day mortality compared with delayed source control.
The CLASSIC Trial: no difference in outcome including adverse events between restrictive versus standard fluid strategies in patients with septic shock.
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