Infectious Disease & Sepsis

From IDWeek Meeting

In a study of 61,000 patients with skin and soft tissue infections across 92 hospitals, a computerized physician order entry (CPOE) system with prompts was compared to standard care with routine antibiotic stewardship. The CPOE intervention, which provided real-time, patient-specific risk estimates, reduced extended-spectrum and antipseudomonal antibiotic use by 28%, without affecting safety outcomes or length of stay. These results suggest that automated, patient-specific tools can effectively promote high-value care and reduce unnecessary antibiotic use in hospitals.

From IDWeek Meeting: The BALANCE Trial compared 7-day vs. 14-day antibiotic regimens in 3600 patients with bloodstream infections across seven countries. Excluding patients with Staphylococcus aureus, fungal infections, severe immunocompromise, or prosthetic heart valves, the trial found that 7-day treatment was noninferior to 14-day treatment for 90-day mortality (14.5% vs. 16.1%). Length of stay was shorter in the 7-day group. These findings support shorter antibiotic courses in appropriate patients, though certain high-risk groups were not included.

I finished Evidence-based Management of Sepsis & Septic Shock! 🚀

Informative , interseted and invaluabe course thanks Dr. Mazen

What do you see here?