Immediate versus staged complete revascularisation in patients presenting with acute coronary syndrome and multivessel coronary disease (BIOVASC): a prospective, open-label, non-inferiority, randomised trial:
The article reports the results of a randomised trial that compared two strategies of complete revascularisation for patients with acute coronary syndrome and multivessel coronary disease: immediate or staged.
The trial enrolled 1525 patients from 29 hospitals across four European countries and randomly assigned them to either receive complete revascularisation (including non-culprit lesions) during the index procedure (immediate group) or within 30 days after the index procedure (staged group).
The primary outcome was a composite of all-cause mortality, myocardial infarction, and unplanned ischaemia-driven revascularisation at 1 year after the index procedure.
The trial found that immediate complete revascularisation was non-inferior to staged complete revascularisation for the primary outcome, with a hazard ratio of 0·78 (95% CI 0·55–1·11, p non-inferiority =0·0011).
The trial also found that immediate complete…
