Insights | ICU REACH

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INSIGHTS

The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!

Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19

Mazen Kherallah

Aug 1, 20223 min read

Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19

Sabizabulin reduced 60-day all-cause mortality in hospitalized patients with moderate to severe COVID-19 infection

Hypothermic versus Normothermic Temperature Control after Cardiac Arrest

Mazen Kherallah

Jul 4, 20223 min read

Neurocritical Care

Hypothermic versus Normothermic Temperature Control after Cardiac Arrest

 Hypothermia at 33°C does not reduce 6-month mortality and does not improve 6-month neurological outcome compared to normothermia.

Diastolic Shock Index: What it Means and how is it Interpreted?

Mazen Kherallah

Jul 3, 20223 min read

Diastolic Shock Index: What it Means and how is it Interpreted?

it seems appropriate to monitor DSI in septic patients due to its prognostic value and ability to guide early administration of vasopressors

Vasopressors in Septic Shock: Timing, Choice & Target

Mazen Kherallah

Jun 8, 20224 min read

Vasopressors in Septic Shock: Timing, Choice & Target

The majority of clinical trials on vasopressor use in septic shock have focused on one of three areas, the timing of vasopressor...

Short vs. Long Antibiotic Course for Ventilator-associated Pneumonia (VAP) and Pseudomonas VAP

Mazen Kherallah

May 22, 20225 min read

Short vs. Long Antibiotic Course for Ventilator-associated Pneumonia (VAP) and Pseudomonas VAP

Ventilator-associated pneumonia is the most common infection among the critically ill patients as it accounts for about 25% of infections

Evolution of Evidence for use of HES in Sepsis & Septic Shock

Mazen Kherallah

May 5, 20223 min read

Evolution of Evidence for use of HES in Sepsis & Septic Shock

Fluid resuscitation with HES 130/0.42 in patients with severe sepsis is associated with an increased risk of death at day 90.

Approach to Vasopressor Support in Septic Shock

Mazen Kherallah

Apr 23, 20226 min read

Approach to Vasopressor Support in Septic Shock

Approach to Vasopressor Support in Septic Shock

Dexmedetomidine vs. Propofol as the Primary Agent for Sedation in General ICU Patients and in Sepsis

Mazen Kherallah

Apr 17, 20225 min read

Dexmedetomidine vs. Propofol as the Primary Agent for Sedation in General ICU Patients and in Sepsis

Dexmedetomidine is in equipoise position with propofol as the primary agent for sedation in general ICU Patients and in Sepsis

Prone Position in ARDS

Mazen Kherallah

Apr 10, 20223 min read

Prone Position in ARDS

Some 60-75% of patients with ARDS have significantly improved oxygenation when turned from the supine to the prone position.

Early Use of Ivermectin Does Not Reduce Progression of COVID-19 Disease!

Mazen Kherallah

Apr 1, 20221 min read

Early Use of Ivermectin Does Not Reduce Progression of COVID-19 Disease!

Early Use of Ivermectin Does Not Reduce Progression of COVID-19 Disease!

Albumin Use in Sepsis & Septic Shock

Mazen Kherallah

Mar 23, 20224 min read

Albumin Use in Sepsis & Septic Shock

Whether albumin is associated with reduced mortality in the resuscitation of septic shock compared with crystalloid is a matter of debate

Evolving Evidence for Steroids in ARDS

Mazen Kherallah

Mar 16, 20223 min read

Evolving Evidence for Steroids in ARDS

The topic of steroid use in ARDS remains a continued interest and debate. DEXA-ARDS and the COVID-19 RECOVERY trials have reintroduced this

Balanced Fluid or Saline for Critically-ill Patients?

Mazen Kherallah

Mar 6, 20224 min read

Fluid & Electrolytes

Balanced Fluid or Saline for Critically-ill Patients?

The absence of robust data led to controversy over the use of crystalloid fluid compared to saline in critically ill patients. This...

Prevention and Treatment of Shivering during Targeted Temperature Management

Mazen Kherallah

Mar 1, 20223 min read

Neurocritical Care

Prevention and Treatment of Shivering during Targeted Temperature Management

Interventions to prevent shivering should be started prior to the initiation of therapeutic hypothermia protocol and prior to any attempt to

Iatrogenic Pneumothorax Caused by NG Tube Placement

Mazen Kherallah

Feb 24, 20225 min read

Respiratory Failure

Iatrogenic Pneumothorax Caused by NG Tube Placement

Iatrogenic pneumothorax is a patient safety indicator (PSI) condition. It is a traumatic pneumothorax secondary to an invasive procedure...

Evolving Evidence for Lung Recruitment Maneuvers in ARDS

Mazen Kherallah

Feb 16, 20227 min read

Evolving Evidence for Lung Recruitment Maneuvers in ARDS

Lung recruitment maneuver employs a transient increase in pressure aiming to open recruitable alveoli and keep them open with PEEP

Airway Pressure Release Ventilation: Settings and Adjustments for Protective Lung Strategy

Mazen Kherallah

Feb 9, 20226 min read

Mechanical Ventilation

Airway Pressure Release Ventilation: Settings and Adjustments for Protective Lung Strategy

Airway Pressure Release Ventilation (APRV) is a recruitment mode that provides a high mean airway pressure and maintain lung protection.

5 Steps in the Assessment of Acid-base Disorders

Mazen Kherallah

Jan 31, 20223 min read

Respiratory Failure

5 Steps in the Assessment of Acid-base Disorders

The accurate interpretation of arterial blood gases is crucial in critically ill patients.

A Paradigm Shift in ICU Sedation

Mazen Kherallah

Jan 25, 20223 min read

Mechanical Ventilation

A Paradigm Shift in ICU Sedation

A tool that can help the clinician to guide therapeutic interventions and minimize sedation and analgesia. for ICU patients

Feedback Mechanism in Volume Support Ventilation

Mazen Kherallah

Jan 18, 20223 min read

Mechanical Ventilation

Feedback Mechanism in Volume Support Ventilation

Volume support (VS) ventilation is a variable pressure support that targets a preset tidal volume. It is a spontaneously triggered mode wher

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