Hypothermic versus Normothermic Temperature Control after Cardiac Arrest
Hypothermia at 33°C does not reduce 6-month mortality and does not improve 6-month neurological outcome compared to normothermia.
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Mazen Kherallah
Jul 3, 20223 min read
Diastolic Shock Index: What it Means and how is it Interpreted?
it seems appropriate to monitor DSI in septic patients due to its prognostic value and ability to guide early administration of vasopressors
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Mazen Kherallah
Jun 8, 20224 min read
Vasopressors in Septic Shock: Timing, Choice & Target
The majority of clinical trials on vasopressor use in septic shock have focused on one of three areas, the timing of vasopressor...
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Mazen Kherallah
May 22, 20225 min read
Short vs. Long Antibiotic Course for Ventilator-associated Pneumonia (VAP) and Pseudomonas VAP
Ventilator-associated pneumonia is the most common infection among the critically ill patients as it accounts for about 25% of infections
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Mazen Kherallah
May 5, 20223 min read
Evolution of Evidence for use of HES in Sepsis & Septic Shock
Fluid resuscitation with HES 130/0.42 in patients with severe sepsis is associated with an increased risk of death at day 90.
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Mazen Kherallah
Apr 23, 20226 min read
Approach to Vasopressor Support in Septic Shock
Approach to Vasopressor Support in Septic Shock
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Mazen Kherallah
Apr 17, 20225 min read
Dexmedetomidine vs. Propofol as the Primary Agent for Sedation in General ICU Patients and in Sepsis
Dexmedetomidine is in equipoise position with propofol as the primary agent for sedation in general ICU Patients and in Sepsis
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Mazen Kherallah
Apr 10, 20223 min read
Prone Position in ARDS
Some 60-75% of patients with ARDS have significantly improved oxygenation when turned from the supine to the prone position.
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Mazen Kherallah
Apr 1, 20221 min read
Early Use of Ivermectin Does Not Reduce Progression of COVID-19 Disease!
Early Use of Ivermectin Does Not Reduce Progression of COVID-19 Disease!
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Mazen Kherallah
Mar 23, 20224 min read
Albumin Use in Sepsis & Septic Shock
Whether albumin is associated with reduced mortality in the resuscitation of septic shock compared with crystalloid is a matter of debate
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Mazen Kherallah
Mar 16, 20223 min read
Evolving Evidence for Steroids in ARDS
The topic of steroid use in ARDS remains a continued interest and debate. DEXA-ARDS and the COVID-19 RECOVERY trials have reintroduced this
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Mazen Kherallah
Mar 6, 20224 min read
Balanced Fluid or Saline for Critically-ill Patients?
The absence of robust data led to controversy over the use of crystalloid fluid compared to saline in critically ill patients. This...
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Mazen Kherallah
Mar 1, 20223 min read
Prevention and Treatment of Shivering during Targeted Temperature Management
Interventions to prevent shivering should be started prior to the initiation of therapeutic hypothermia protocol and prior to any attempt to
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Mazen Kherallah
Feb 24, 20225 min read
Iatrogenic Pneumothorax Caused by NG Tube Placement
Iatrogenic pneumothorax is a patient safety indicator (PSI) condition. It is a traumatic pneumothorax secondary to an invasive procedure...
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Mazen Kherallah
Feb 16, 20227 min read
Evolving Evidence for Lung Recruitment Maneuvers in ARDS
Lung recruitment maneuver employs a transient increase in pressure aiming to open recruitable alveoli and keep them open with PEEP
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Mazen Kherallah
Feb 9, 20226 min read
Airway Pressure Release Ventilation: Settings and Adjustments for Protective Lung Strategy
Airway Pressure Release Ventilation (APRV) is a recruitment mode that provides a high mean airway pressure and maintain lung protection.
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Mazen Kherallah
Jan 31, 20223 min read
5 Steps in the Assessment of Acid-base Disorders
The accurate interpretation of arterial blood gases is crucial in critically ill patients.
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Mazen Kherallah
Jan 25, 20223 min read
A Paradigm Shift in ICU Sedation
A tool that can help the clinician to guide therapeutic interventions and minimize sedation and analgesia. for ICU patients
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Mazen Kherallah
Jan 18, 20223 min read
Feedback Mechanism in Volume Support Ventilation
Volume support (VS) ventilation is a variable pressure support that targets a preset tidal volume. It is a spontaneously triggered mode wher
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Mazen Kherallah
Jan 14, 20224 min read
Patient-Ventilator Interaction & Asynchrony
Patient-ventilator asynchrony (PVA) is a mismatch between the patient's demand and the ventilator during a ventilator breath delivery.
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