CLASSIC vs CLOVERS Trial for Fluid Strategy
The results of the CLOVERS trial are now released at NEJM and revealed that 90-day mortality is not different between conservative fluid...
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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Mazen Kherallah
Jan 18, 20234 min read
Use of Anesthetic Conserving Devices in ICU Sedation
Critical care is shifting towards using volatile anesthetics such as isoflurane and sevoflurane as sedatives for patients on mechanical...
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Mazen Kherallah
Dec 6, 20226 min read
Sedation Algorithm for Intubated Patients
The above algorithm is developed based on the society of critical care medicine PADIS guidelines with overall objectives to: Address pain...
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Mazen Kherallah
Nov 12, 20224 min read
COVID-19 Treatment Update
The pathogenesis of COVID-19 is driven by two main processes: replication of SARS-CoV-2 and a dysregulated immune/inflammatory response....
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Mazen Kherallah
Nov 11, 20223 min read
Cough Assist in Mechanically Ventilated Patients
Mechanical insufflation-exsufflation is a technique that uses pressure to help clear secretions from the lungs. There is limited evidence on
2270
Mazen Kherallah
Nov 5, 20225 min read
Neurological Prognostication after Cardiac Arrest: What Every Intensivist Should Know!
Determination of poor neurological prognosis after cardiac arrest can be best done at least 72 hours after ROSC
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Mazen Kherallah
Oct 27, 20225 min read
The PILOT Trial and Evolution of Evidence for Oxygen Targets in the Critically Ill Patients
It appears that there is no significant difference in mortality or other outcomes when critically ill patients are given a conservative oxyg
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Mazen Kherallah
Oct 25, 20227 min read
Selection of Paralytic and Induction Agents in RSI
Selection of a paralytic and induction agents in rapid sequence intubation (RSI).
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Mazen Kherallah
Oct 18, 20223 min read
Evolution on Evidence for ECCO2R Use in ARDS Patients
Even though extracorporeal CO2 removal might appear appealing because it helps reduce the mechanical force of ventilation, evidence showed
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Mazen Kherallah
Oct 14, 20225 min read
Echocardiographic Signs of Right Ventricular Strain in Acute Pulmonary Embolism
Right ventricular (RV) strain, as seen on echocardiography, is a common finding in patients with pulmonary embolism (PE). This is due to...
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Mazen Kherallah
Oct 9, 20225 min read
High Peak Inspiratory Pressure Troubleshooting
Patients on the volume control mode of ventilation may have an increased peak pressure that could be due to increased airway resistance,
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Mazen Kherallah
Oct 8, 20224 min read
P 0.1 Predicts Respiratory Drive in Patients on Mechanical Ventilation
The respiratory drive is the intensity of the neural stimulus that determines how much the respiratory muscles contract
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Mazen Kherallah
Oct 4, 20223 min read
Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis
aggressive fluid resuscitation in the treatment of acute pancreatitis was found to be linked with a higher risk of volume overload
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Mazen Kherallah
Oct 3, 20223 min read
Strategies to Implement Early Mobility Programs Successfully in the ICU
In conclusion, the barriers to early mobilization in the ICU are many and varied. This barriers could be related to patient status, organiza
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Mazen Kherallah
Sep 27, 20223 min read
End-expiratory Occlusion test and the assessment of transpulmonary pressure
EEO test is the pressure generated by the inspiratory effort of the patient against occluded airway.
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Mazen Kherallah
Sep 23, 20225 min read
How End-expiratory Occlusion test (EEO) Test Can Help Assess Fluid Responsiveness in ICU Patients!
The End-Expiratory Occlusion Test is a reliable tool used by clinicians to assess fluid responsiveness in ICU patients. The test can be used
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Mazen Kherallah
Sep 23, 20225 min read
Burnout Syndrome among ICU Healthcare Professionals
Critical care health professionals are at high risk for burnout syndrome. This debilitating condition can cause physical and emotional...
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Mazen Kherallah
Sep 18, 20224 min read
Ultrasound Assessment of Spontaneous Effort on Mechanical Ventilation
Us if ultrasound of the diaphragm to identify spontaneous inspiratory efforts and facilitate protection of lungs and diaphragm
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Mazen Kherallah
Sep 6, 20223 min read
Should We Use a Higher Blood-Pressure Target in Comatose Survivors of Cardiac Arrest?
Higher mean arterial pressure in patients after cardiac arrest does not improve outcome
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Mazen Kherallah
Aug 1, 20223 min read
Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19
Sabizabulin reduced 60-day all-cause mortality in hospitalized patients with moderate to severe COVID-19 infection
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