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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Ventricular Pressure-volume Loop in Normal Heart
The pressure-volume loop and its parameters (EDVPR, ESVPR, Ea, Ea/Ees) assess heart function, aiding decisions and improving outcomes
Mazen Kherallah
May 19, 20248 min read
2,735
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Advanced CT Perfusion Imaging in Stroke Management: A Detailed Insight
CT perfusion imaging enhances stroke diagnosis and treatment, improving outcomes by identifying specific brain perfusion patterns.
Mazen Kherallah
May 7, 20243 min read
207
6

The Silent Sacrifices of the Intensivist!
This narrative highlights the unspoken hardships and dedication of healthcare workers, who serve not for glory but to make a difference.
Mazen Kherallah
Apr 13, 20243 min read
282
1

What is the Evidence for Contrast-induced Nephropathy (CIN)?
Recent research shows minimal CIN risk from CT contrast, with strategies in place for prevention and ensuring safety.
Mazen Kherallah
Apr 11, 20244 min read
288
3


The Critical Need for Standardizing Norepinephrine Formulation Reporting in Intensive Care
This study underscores the need for standardized norepinephrine reporting to improve care and research in critical care medicine globally.
Mazen Kherallah
Mar 17, 20243 min read
399
2

Etomidate versus Ketamine for RSI
Recent findings suggest ketamine may lower mortality compared to etomidate, but study limitations remain.
Mazen Kherallah
Mar 11, 20242 min read
793
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What is Reverse Triggering?
Reverse triggering in ventilation is reflexive patient breathing due to ventilator stimuli, requiring careful management to avoid lung stre
Mazen Kherallah
Jan 28, 20243 min read
1,074
2

The Impact of Balanced Crystalloids vs. Saline in ICU Patients: A New Meta-Analysis
Balanced crystalloids vs. saline in ICU show 89.5% benefit probability but debate continues.
Mazen Kherallah
Jan 24, 20243 min read
388
1

Unveiling the Impact of Corticosteroids in Community-Acquired Pneumonia: A Comprehensive Meta-Analysis
Meta-analysis reveals corticosteroids reduce CAP mortality, especially in severe cases, highlighting tailored therapy benefits
Mazen Kherallah
Jan 22, 20243 min read
265
1


Contemplating Lytic Therapy in a Complex Case of Respiratory Decompensation!
Massive pulmonary embolism
Mazen Kherallah
Jan 4, 20242 min read
322
3


Hypothermia vs Normothermia in Patients With Cardiac Arrest and Nonshockable Rhythm
Evidence supports using normothermia in patients with coma after cardiac arrest with nonshockable rhythm compared to hypothermia.
Mazen Kherallah
Dec 28, 20235 min read
398
2


Cefepime or Piperacillin/tazobactam Empirically for Gram-negative Infections in the Hospital settings
This trial suggests comparable risks of acute kidney injury and death between cefepime and piperacillin/tazobactam.
Mazen Kherallah
Dec 23, 20233 min read
924
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Doing Less is Actually Doing More: The NICO Trial!
In cases of coma due to acute poisoning, a conservative airway management strategy could be more beneficial than routine intubation.
Mazen Kherallah
Dec 6, 20232 min read
1,242
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Restrictive vs Liberal Transfusion Strategy in Patients with Myocardial Infarction and Anemia
A liberal transfusion strategy did not significantly reduce the risk of recurrent myocardial infarction or death at 30 days in MI and anemia
Mazen Kherallah
Nov 15, 20234 min read
515
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β-blockers and Sepsis (The STRESS-L Trial)
β-blockers do not improve outcomes in septic shock and maybe harmful
Mazen Kherallah
Nov 11, 20232 min read
489
5

Bayesian Analysis Simplified!
Bayesian analysis integrates prior knowledge with current evidence to come closer to the truth.
Mazen Kherallah
Nov 6, 20233 min read
212
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Would you Consider Using Inhaled Amikacin to Prevent from VAP?
Inhaled amikacin could be a viable option for preventing VAP in patients who are on mechanical ventilation for longer than 72 hours.
Mazen Kherallah
Oct 31, 20233 min read
1,115
1


Diminishing Utilization of Prone Positioning for Severe ARDS Patients After COVID-19
The findings underscore a concerning downtrend in the use of prone positioning for managing severe ARDS in COVID-19 patients.
Mazen Kherallah
Oct 13, 20232 min read
182
1


Should early lumbar cerebrospinal fluid drain be considered for aneurysmal subarachnoid hemorrhage?
Early lumbar cerebrospinal fluid drainage should be considered for patients following an aneurysmal subarachnoid hemorrhage.
Mazen Kherallah
Sep 29, 20233 min read
365
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Ultrasound-Guided CVC: Biplane vs. Single-Plane Approaches
Biplane ultrasound-guided method is notably superior to the single-plane technique.
Mazen Kherallah
Sep 27, 20232 min read
584
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