Mechanical Thrombectomy in Pulmonary Embolism: Insights from the PEERLESS Trial
The PEERLESS trial provides compelling evidence that LBMT offers an effective and safe alternative to CDT for intermediate-risk PE patients.
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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Mazen Kherallah
Nov 126 min read
Time vs Volume Capnography
Volume capnography represents CO₂ concentration against expired volume allowing to account for dead space and CO2 production.
1620
Mazen Kherallah
Nov 43 min read
Understanding the VExUS Score: A Case Example of Grade 3 Congestion
Grade 3 VExUS score indicating severe venous congestion.
1610
Mazen Kherallah
Oct 263 min read
Strategies for Successful Weaning from Mechanical Ventilation: What the Latest Research Reveals?
Burns et al. highlight that once-daily screening with pressure-supported SBTs may optimize ICU weaning, guiding personalized critical care.
3882
Mazen Kherallah
Oct 232 min read
Liberal vs. Restrictive Transfusion Strategies in TBI: A New Perspective!
Based on the TRAIN and HEMOTION trials, liberal transfusion thresholds should be advocated for neurocritically ill patients.
1453
Mazen Kherallah
Sep 303 min read
SGLT2 Inhibitors Likely Reduce the Incidence of Ventricular Arrhythmias in Heart Failure!
the current evidence supports the integration of SGLT2 inhibitors into treatment protocols for patients with heart failure.
690
Mazen Kherallah
Aug 183 min read
One- or two-week Patient-intensivist Continuity of Care in the ICU?
Current evidence does not strongly support extending intensivist continuity from one to two weeks for ICU patients in terms of outcomes
801
Mazen Kherallah
Aug 143 min read
The Impact of Intensive Glucose Control in Critically Ill Patients: Insights from a Comprehensive Meta-Analysis
intensive glucose control does not improve survival in critically ill adults and may even pose significant risks of hypoglycemia.
1490
Mazen Kherallah
Aug 13 min read
The Impact of In-Hospital Violence on Critical Care Practitioners: A Growing Crisis!
In-hospital violence is a growing concern for healthcare facilities, impacting the physical and mental well-being of physicians
481
Mazen Kherallah
Jul 243 min read
Tenecteplase in Extended Window: A Promising Alternative for Acute Stroke Treatment!
Tenecteplase is an alternative option in in patients with acute stroke without immediate access to thrombectomy.
1420
Mazen Kherallah
Jul 83 min read
New Oral Agent for Hereditary Angioedema Treatment: Sebetralstat
Oral sebetralstat represents a leap forward in the management of hereditary angioedema, providing patients with a more accessible and effect
941
Mazen Kherallah
Jun 292 min read
Ventricular-Arterial Coupling (Ea/Ees Ratio)
Ventricular-arterial coupling is a dynamic interplay between ventricular contractility and arterial load.
5040
Mazen Kherallah
Jun 193 min read
Does Achieving Better β-lactam Pharmacokinetic Targets Translate to Better Clinical Outcomes in Septic Patients?
Continuous infusion of β-lactam antibiotics holds promise for better outcomes in sepsis treatment.
2530
Mazen Kherallah
Jun 162 min read
Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation
PPIs can reduce gastrointestinal bleeding and possibly mortality in less severely ill patients, they do not significantly impact mortality.
2840
Mazen Kherallah
Jun 92 min read
Post-Spontaneous Breathing Trial Reconnection to Mechanical Ventilation for Alveolar Recruitment Recovery
These findings highlight the importance of post-SBT reconnection in recovering alveolar derecruitment after SBT.
2173
Mazen Kherallah
May 293 min read
Understanding Preload of the Left Ventricle: A Key Concept in Cardiovascular Physiology
Preload is a fundamental concept in cardiovascular physiology, essential for understanding the mechanics of the heart. It refers to the...
2590
Mazen Kherallah
May 263 min read
Hemodynamic Profile in Sepsis and Septic Shock Associated with Vasoplegia: A Pressure-Volume Diagram Perspective
Sepsis is a life-threatening condition characterized by an overwhelming immune response to infection, leading to widespread inflammation...
5240
Mazen Kherallah
May 223 min read
AI in Critical Care Medicine
AI's integration into critical care medicine offers substantial benefits but also presents challenges that need to be addressed.
1360
Mazen Kherallah
May 198 min read
Ventricular Pressure-volume Loop in Normal Heart
The pressure-volume loop and its parameters (EDVPR, ESVPR, Ea, Ea/Ees) assess heart function, aiding decisions and improving outcomes
1,3410
Mazen Kherallah
May 73 min read
Advanced CT Perfusion Imaging in Stroke Management: A Detailed Insight
CT perfusion imaging enhances stroke diagnosis and treatment, improving outcomes by identifying specific brain perfusion patterns.
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